Nature and extend
نویسندگان
چکیده
Some Azomethines of 5-amino isophthalic acid were synthesized and their antibacterial activity was studied in DMSO against four Gram positive Bacillus cereus ATCC11778, Staphylococcus aureus ATCC29737, Staphylococcus epidermidids NCIM2493 and Micrococcus luteus ATCC10240, and three Gram negative bacteria viz. Proteus mirabilis NCIM2241, Escherichia coli ATCC25922 and Klebsiella aerogenes NICM2098 bacteria. The antibacterial activity was done using Agar well diffusion method. The azomethines showed different activity against different bacterial strains depending on their structural formula. Among Gram positive bacteria, Micrococcus luteus was the most resistant bacteria and Bacillus cereus was the most susceptible bacteria. Whereas among Gram negative bacteria. E. coli was the most resistant bacteria. The presence of vanillin side chain and chloro benzaldehyde were found be more effective against Gram positive and Gram negative bacteria
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